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Resveratrol has been found to possess numerous
potential health-related benefits including:
Lowering cholesterol
Protecting heart and circulatory system
Protects the brain
Helps to lower blood sugar levels
Increases Insulin Sensitivity
About Resveratrol:
Resveratrol is a naturally occurring compound
called a polyphenol and is present in a number of common food items such as
berries, grapes, vine, peanuts, etc. Plants that produce resveratrol do so
partly as a protective mechanism and response to stressors within their
environments, including the presence of insects or other predators, damage,
injury, and fungal varieties. Resveratrol is believed to be one of the most
potent polyphenols and a strong protector against aging and free radical
damage. buy
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The benefits of resveratrol were first
discovered when researchers established that a variety of yeasts, microbes,
insects and animals that were fed resveratrol experienced an increased
lifespan. Several studies continued to confirm these longevity and anti-aging
benefits, in their successful work on flies, fish, mice and nematode worms, all
of which lived longer compared to control groups that were not treated with
this phytonutrient.
Being a part of the polyphenol group,
Resveratrol possesses antioxidant properties that are believed to help prevent
the formation of cancerous cells.
How Does Resveratrol Work?
Resveratrol works as anti-oxidant and fights
free radicals which contribute towards increased aging. Resveratrol can either
passively cross cell membranes or interact with its receptors due to its unique
physical and chemical properties, making it possible for Resveratrol to
interact with inter and extracellular molecules effortlessly. It is because of
this that its mechanism of action is triggered by one of the two means (at a
cellular level):
By developing its effect inside the nucleus
Activating intracellular mechanism by first
activating signalled pathways when binding to receptors of the cell membrane
The way it functions as an anti-aging substance can
possibly be explained how it activates SIRT. A study suggests that it can
directly activate NMNAT enzyme which increases the intracellular activity and
levels of NAD+ which is likely to affect SIRT which primarily requires the
presence of NAD+ in order to function. In another experiment, human cells were
treated with Resveratrol independent of NMNAT enzyme. Even without the presence
of NMNAT, Resveratrol still rejuvenated old cells which started to divide and
develop longer telomeres with the restoration of the splicing factor
expression. The cells not only started to appear younger but behaved more like
younger cells as well.
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